The Argentina international has been out of action since suffering an adductor injury in Barca’s 1-1 draw with Atletico Madrid on Sept. 21.
Arda Turan continues to deputize in the starting XI as the Catalan giants seek their fifth win of the season.
Barcelona starting XI: Ter Stegen; Digne, Pique, Mascherano, Mathieu; Rakitic, Busquets, Rafinha; Arda, L. Suarez, Neymar
Subs: Masip, Umtiti, Iniesta, Andre Gomes, D. Suarez, Messi, Alcacer